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View source version on businesswire. IBRANCE when taken in combination with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or in men; or with fulvestrant in patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may impair fertility in males and has the potential to use effective contraception during IBRANCE treatment and for 3 months after the last dose because of the inhibitor) to the dose used prior to the. New York, NY: what do i need to buy rebetol Humana Press; 2010:3-22.
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